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Open Access

Peer-reviewed

Research Article

Isorhamnetin Attenuates Atherosclerosis by Inhibiting Macrophage Apoptosis via PI3K/AKT Activation and HO-1 Induction

Yun Luo,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China
⨯
Guibo Sun ,

* E-mail: sunguibo@126.com (GBS); sun_xiaobo163@163.com (XBS)

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China
⨯
Xi Dong,

Affiliation Academy of Chinese Materia Medica, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Min Wang,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China
⨯
Meng Qin,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China
⨯
Yingli Yu,

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China
⨯
Xiaobo Sun

* E-mail: sunguibo@126.com (GBS); sun_xiaobo163@163.com (XBS)

Affiliation Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, PR China
⨯

Isorhamnetin Attenuates Atherosclerosis by Inhibiting Macrophage Apoptosis via PI3K/AKT Activation and HO-1 Induction

Yun Luo,
Guibo Sun,
Xi Dong,
Min Wang,
Meng Qin,
Yingli Yu,
Xiaobo Sun

x

Published: March 23, 2015
https://doi.org/10.1371/journal.pone.0120259

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Macrophages
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Apoptosis
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Atherosclerosis
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Lipids
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Oils
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Oxidative stress
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Cell viability testing
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Mitochondria
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