Effect of Fatty Acids on Human Bone Marrow Mesenchymal Stem Cell Energy Metabolism and Survival

Natasha Fillmore; Alda Huqi; Jagdip S. Jaswal; Jun Mori; Roxane Paulin; Alois Haromy; Arzu Onay-Besikci; Lavinia Ionescu; Bernard Thébaud; Evangelos Michelakis; Gary D. Lopaschuk

doi:10.1371/journal.pone.0120257

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Open Access

Peer-reviewed

Research Article

Effect of Fatty Acids on Human Bone Marrow Mesenchymal Stem Cell Energy Metabolism and Survival

Natasha Fillmore,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Alda Huqi,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Jagdip S. Jaswal,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Jun Mori,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Roxane Paulin,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Alois Haromy,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Arzu Onay-Besikci,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Lavinia Ionescu,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Bernard Thébaud,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Evangelos Michelakis,

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯
Gary D. Lopaschuk

* E-mail: gary.lopaschuk@ualberta.ca

Affiliation Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada
⨯

Effect of Fatty Acids on Human Bone Marrow Mesenchymal Stem Cell Energy Metabolism and Survival

Natasha Fillmore,
Alda Huqi,
Jagdip S. Jaswal,
Jun Mori,
Roxane Paulin,
Alois Haromy,
Arzu Onay-Besikci,
Lavinia Ionescu,
Bernard Thébaud,
Evangelos Michelakis

Published: March 13, 2015
https://doi.org/10.1371/journal.pone.0120257

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Fatty acids
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Mesenchymal stem cells
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Oxidation
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Oleates
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Glycolysis
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Stem cell therapy
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Energy metabolism
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Albumins
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