Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro

Open Access

Peer-reviewed

Research Article

Melanie S. Brennan,

Affiliation Department of Neurology Research, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯
Maria F. Matos,

Affiliation Department of Neurology Research, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯
Bing Li,

Affiliation Department of Neurology Research, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯
Xiaoping Hronowski,

Affiliation Department of Discovery Proteomics and Mass Spectrometry, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯
Benbo Gao,

Affiliation Department of Discovery Proteomics and Mass Spectrometry, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯
Peter Juhasz,

Affiliation Department of Discovery Proteomics and Mass Spectrometry, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯
Kenneth J. Rhodes,

Affiliation Department of Neurology Research, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯
Robert H. Scannevin

* E-mail: robert.scannevin@biogenidec.com

Affiliation Department of Neurology Research, Biogen Idec, Inc., Cambridge, MA, United States of America
⨯

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