A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats

Yuanyuan Qian; Peng Zhong; Dandan Liang; Zheng Xu; Melissa Skibba; Chunlai Zeng; Xiaokun Li; Tiemin Wei; Lianpin Wu; Guang Liang

doi:10.1371/journal.pone.0120215

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Open Access

Peer-reviewed

Research Article

A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats

Yuanyuan Qian ,

Contributed equally to this work with: Yuanyuan Qian, Peng Zhong

Affiliation Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Peng Zhong ,

Contributed equally to this work with: Yuanyuan Qian, Peng Zhong

Affiliations Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China, Department of Cardiology, the 5th Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, China
⨯
Dandan Liang,

Affiliation Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Zheng Xu,

Affiliation Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Melissa Skibba,

Affiliation Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Chunlai Zeng,

Affiliation Department of Cardiology, the 5th Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, China
⨯
Xiaokun Li,

Affiliation Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Tiemin Wei,

Affiliation Department of Cardiology, the 5th Affiliated Hospital of Wenzhou Medical University, Lishui, Zhejiang, China
⨯
Lianpin Wu ,

* E-mail: wzwlp@sina.com (LW); wzmcliangguang@163.com (GL)

Affiliation Department of Cardiology, the 2nd Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯
Guang Liang

* E-mail: wzwlp@sina.com (LW); wzmcliangguang@163.com (GL)

Affiliation Chemical Biology Research Center, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, Zhejiang, China
⨯

A Newly Designed Curcumin Analog Y20 Mitigates Cardiac Injury via Anti-Inflammatory and Anti-Oxidant Actions in Obese Rats

Yuanyuan Qian,
Peng Zhong,
Dandan Liang,
Zheng Xu,
Melissa Skibba,
Chunlai Zeng,
Xiaokun Li,
Tiemin Wei,
Lianpin Wu,
Guang Liang

Published: March 18, 2015
https://doi.org/10.1371/journal.pone.0120215

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