Breaking the Hydrophobicity of the MscL Pore: Insights into a Charge-Induced Gating Mechanism

Open Access

Peer-reviewed

Research Article

Balasubramanian Chandramouli,

Affiliation Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126, Pisa, Italy
⨯
Danilo Di Maio,

Affiliations Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126, Pisa, Italy, Istituto Nazionale di Fisica Nucleare (INFN), sezione di Pisa, Largo Bruno Pontecorvo 3, 56127, Pisa, Italy
⨯
Giordano Mancini,

Affiliations Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126, Pisa, Italy, Istituto Nazionale di Fisica Nucleare (INFN), sezione di Pisa, Largo Bruno Pontecorvo 3, 56127, Pisa, Italy
⨯
Vincenzo Barone,

Affiliations Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126, Pisa, Italy, Istituto Nazionale di Fisica Nucleare (INFN), sezione di Pisa, Largo Bruno Pontecorvo 3, 56127, Pisa, Italy
⨯
Giuseppe Brancato

* E-mail: giuseppe.brancato@sns.it

Affiliations Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126, Pisa, Italy, Istituto Nazionale di Fisica Nucleare (INFN), sezione di Pisa, Largo Bruno Pontecorvo 3, 56127, Pisa, Italy
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Ion channel gating
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Radii
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Biochemical simulations
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Electrostatics
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Crystal structure
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Ions
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Lipids
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Membrane structures
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