Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction

Jin Chai; Xinchan Feng; Liangjun Zhang; Sheng Chen; Ying Cheng; Xiaochong He; Yingxue Yang; Yu He; Huaizhi Wang; Rongquan Wang; Wensheng Chen

doi:10.1371/journal.pone.0120055

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Open Access

Peer-reviewed

Research Article

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction

Jin Chai,

Affiliation Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Xinchan Feng,

Affiliation Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Liangjun Zhang,

Affiliation Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Sheng Chen,

Affiliation Department of Pediatrics, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Ying Cheng,

Affiliation Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Xiaochong He,

Affiliation School of Nursing, Third Military Medical University, Chongqing, P.R. China
⨯
Yingxue Yang,

Affiliation Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan, P.R. China
⨯
Yu He,

Affiliation Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Huaizhi Wang,

Affiliation Institute of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Rongquan Wang,

Affiliation Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯
Wensheng Chen

* E-mail: wenshengchen@hotmail.com

Affiliation Department of Gastroenterology, Southwest Hospital, Third Military Medical University, Chongqing, P.R. China
⨯

Hepatic Expression of Detoxification Enzymes Is Decreased in Human Obstructive Cholestasis Due to Gallstone Biliary Obstruction

Jin Chai,
Xinchan Feng,
Liangjun Zhang,
Sheng Chen,
Ying Cheng,
Xiaochong He,
Yingxue Yang,
Yu He,
Huaizhi Wang,
Rongquan Wang

Published: March 23, 2015
https://doi.org/10.1371/journal.pone.0120055

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