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Open Access
Peer-reviewed
Research Article
N-Glycomic Changes in Serum Proteins in Type 2 Diabetes Mellitus Correlate with Complications and with Metabolic Syndrome Parameters
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Roberto Testa ,
Contributed equally to this work with: Roberto Testa, Valerie Vanhooren
* E-mail: r.testa@inrca.it
Affiliation Experimental models in Clinical Pathology, Italian National Research Center on Aging (INRCA), Ancona, 60127, Italy
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Valerie Vanhooren ,
Contributed equally to this work with: Roberto Testa, Valerie Vanhooren
Affiliations VIB Inflammation Research Center, Technologiepark 927, B-9052, Ghent, Belgium, Department of Molecular Biology, Ghent University, Technologiepark 927, B-9052, Ghent, Belgium
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Anna Rita Bonfigli,
Affiliation Scientific Direction, Italian National Research Center on Aging (INRCA), Ancona, 60124, Italy
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Massimo Boemi,
Affiliation Metabolic Diseases and Diabetology Unit, Italian National Research Center on Aging (INRCA), 60127, Ancona, Italy
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Fabiola Olivieri,
Affiliations Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, 60020, Italy, Center of Clinical Pathology and Innovative Therapy, Italian National Research Center on Aging (INRCA), Ancona, 60127, Italy
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Antonio Ceriello,
Affiliations Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, 08036, Spain, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, 08017, Spain
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Stefano Genovese,
Affiliation Department of Cardiovascular and Metabolic Diseases, IRCCS Gruppo Multimedica Sesto San Giovanni (MI), 20099, Italy
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Liana Spazzafumo,
Affiliation Center of Biostatistic, Italian National Research Center on Aging (INRCA), Ancona, 60124, Italy
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Vincenzo Borelli,
Affiliation Department of Experimental, Diagnostic and Specialty Medicine Experimental Pathology, University of Bologna, Via S. Giacomo 12, Bologna, 40126, Italy
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Maria Giulia Bacalini,
Affiliation Department of Experimental, Diagnostic and Specialty Medicine Experimental Pathology, University of Bologna, Via S. Giacomo 12, Bologna, 40126, Italy
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Stefano Salvioli,
Affiliation Department of Experimental, Diagnostic and Specialty Medicine Experimental Pathology, University of Bologna, Via S. Giacomo 12, Bologna, 40126, Italy
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Paolo Garagnani,
Affiliations Department of Experimental, Diagnostic and Specialty Medicine Experimental Pathology, University of Bologna, Via S. Giacomo 12, Bologna, 40126, Italy, Center for Applied Biomedical Research, St. Orsola-Malpighi University Hospital, Bologna, 40138, Italy, Interdepartmental Centre "L. Galvani" CIG, University of Bologna, Piazza di Porta S. Donato 1, Bologna, 40126, Italy
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Sylviane Dewaele,
Affiliations VIB Inflammation Research Center, Technologiepark 927, B-9052, Ghent, Belgium, Department of Molecular Biology, Ghent University, Technologiepark 927, B-9052, Ghent, Belgium
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Claude Libert,
Affiliations VIB Inflammation Research Center, Technologiepark 927, B-9052, Ghent, Belgium, Department of Molecular Biology, Ghent University, Technologiepark 927, B-9052, Ghent, Belgium
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Claudio Franceschi
Affiliations Department of Experimental, Diagnostic and Specialty Medicine Experimental Pathology, University of Bologna, Via S. Giacomo 12, Bologna, 40126, Italy, Center for Applied Biomedical Research, St. Orsola-Malpighi University Hospital, Bologna, 40138, Italy, Interdepartmental Centre "L. Galvani" CIG, University of Bologna, Piazza di Porta S. Donato 1, Bologna, 40126, Italy, IRCCS, Institute of Neurological Sciences of Bologna, Bologna, 40124, Italy
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N-Glycomic Changes in Serum Proteins in Type 2 Diabetes Mellitus Correlate with Complications and with Metabolic Syndrome Parameters
- Roberto Testa,
- Valerie Vanhooren,
- Anna Rita Bonfigli,
- Massimo Boemi,
- Fabiola Olivieri,
- Antonio Ceriello,
- Stefano Genovese,
- Liana Spazzafumo,
- Vincenzo Borelli,
- Maria Giulia Bacalini
- Published: March 20, 2015
- https://doi.org/10.1371/journal.pone.0119983