Blockade of the SNARE Protein Syntaxin 1 Inhibits Glioblastoma Tumor Growth

Fausto Ulloa; Alba Gonzàlez-Juncà; Delphine Meffre; Pablo José Barrecheguren; Ramón Martínez-Mármol; Irene Pazos; Núria Olivé; Tiziana Cotrufo; Joan Seoane; Eduardo Soriano

doi:10.1371/journal.pone.0119707

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Open Access

Peer-reviewed

Research Article

Blockade of the SNARE Protein Syntaxin 1 Inhibits Glioblastoma Tumor Growth

Fausto Ulloa ,

* E-mail: fausto.ulloa@ub.edu

Affiliations Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, 28031, Madrid, Spain
⨯
Alba Gonzàlez-Juncà,

Affiliations Translational Research Program, Vall d'Hebron Institute of Oncology (VHIO), Vall d’Hebron University Hospital, 08035, Barcelona, Spain, Universitat Autònoma de Barcelona, 08193, Cerdanyola del Vallès, Spain
⨯
Delphine Meffre,

Affiliation Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain
⨯
Pablo José Barrecheguren,

Affiliations Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain, Institute for Research in Biomedicine (IRB), Cell and Developmental Biology Program, Barcelona, 08028, Spain
⨯
Ramón Martínez-Mármol,

Affiliations Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, 28031, Madrid, Spain
⨯
Irene Pazos,

Affiliation Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain
⨯
Núria Olivé,

Affiliation Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain
⨯
Tiziana Cotrufo,

Affiliations Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, 28031, Madrid, Spain
⨯
Joan Seoane,

Affiliations Translational Research Program, Vall d'Hebron Institute of Oncology (VHIO), Vall d’Hebron University Hospital, 08035, Barcelona, Spain, Universitat Autònoma de Barcelona, 08193, Cerdanyola del Vallès, Spain, Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010, Barcelona, Spain
⨯
Eduardo Soriano

Affiliations Department of Cell Biology, University of Barcelona, Parc Cientific de Barcelona, 08028, Barcelona, Spain, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII, 28031, Madrid, Spain, Vall d´Hebron Institute of Research (VHIR), 08035, Barcelona, Spain, Institució Catalana de Recerca i Estudis Avançats (ICREA), 08010, Barcelona, Spain
⨯

Blockade of the SNARE Protein Syntaxin 1 Inhibits Glioblastoma Tumor Growth

Fausto Ulloa,
Alba Gonzàlez-Juncà,
Delphine Meffre,
Pablo José Barrecheguren,
Ramón Martínez-Mármol,
Irene Pazos,
Núria Olivé,
Tiziana Cotrufo,
Joan Seoane,
Eduardo Soriano

Published: March 24, 2015
https://doi.org/10.1371/journal.pone.0119707

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SNARE proteins
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