Effects of Nutritional Supplementation on Fatigue, and Autonomic and Immune Dysfunction in Patients with End-Stage Renal Disease: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial

• Sanae Fukuda,

  Affiliations University of Welfare Sciences, Kasiwara, Osaka, 582-0026, Japan, RIKEN Center for Life Science Technologies, Kobe, Hyogo, 650-0047, Japan, Department of Physiology, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan

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• Hidenori Koyama ,

  * E-mail: hkoyama@hyo-med.ac.jp

  Affiliations Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan, Department of Internal Medicine, Division of Diabetes, Endocrinology and Metabolism, Hyogo College of Medicine, Nishinomiya, Hyogo, 663-8501, Japan

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• Kazuhiro Kondo,

  Affiliation Department of Virology, The Jikei University School of Medicine, Tokyo, 105-8461, Japan

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• Hisako Fujii,

  Affiliations Department of Physiology, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan, Center for Drug & Food Clinical Evaluation, Osaka City University Hospital, Osaka, 540-0051, Japan

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• Yoshinobu Hirayama,

  Affiliation College of Pharmaceutical Sciences, Ritsumeikan University, Kusatsu, 525-8577, Japan

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• Tsutomu Tabata,

  Affiliation Inoue Hospital, Suita, 564-0053, Japan

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• Mikio Okamura,

  Affiliation Ohno Memorial Hospital, Osaka, 550-0015, Japan

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• Tomoyuki Yamakawa,

  Affiliation Shirasagi Hospital, Osaka, 546-0002, Japan

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• Shigeki Okada,

  Affiliation Okada Clinic, Osaka, 543-0056, Japan

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• Sumio Hirata,

  Affiliation Kumamoto University School of Pharmacy, Kumamoto, 862-0973, Japan

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• Hiroshi Kiyama,

  Affiliation Nagoya University School of Medicine, Nagoya, 466-8550, Japan

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• Osami Kajimoto,

  Affiliation Department of Medical Science on Fatigue, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan

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• Yasuyoshi Watanabe,

  Affiliations RIKEN Center for Life Science Technologies, Kobe, Hyogo, 650-0047, Japan, Department of Physiology, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan

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• Masaaki Inaba,

  Affiliation Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan

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• Yoshiki Nishizawa

  Affiliation Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, 545-8585, Japan

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