Sublingual Immunization of Trivalent Human Papillomavirus DNA Vaccine in Baculovirus Nanovector for Protection against Vaginal Challenge

Hee-Jung Lee; Hansam Cho; Mi-Gyeong Kim; Yoon-Ki Heo; Yeondong Cho; Yong-Dae Gwon; Ki Hoon Park; Hyerim Jin; Jinyoung Kim; Yu-Kyoung Oh; Young Bong Kim

doi:10.1371/journal.pone.0119408

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Open Access

Peer-reviewed

Research Article

Sublingual Immunization of Trivalent Human Papillomavirus DNA Vaccine in Baculovirus Nanovector for Protection against Vaginal Challenge

Hee-Jung Lee,

Affiliation Department of Bio-industrial Technologies, Konkuk University, Seoul, Republic of Korea
⨯
Hansam Cho,

Affiliation Department of Bio-industrial Technologies, Konkuk University, Seoul, Republic of Korea
⨯
Mi-Gyeong Kim,

Affiliation College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea
⨯
Yoon-Ki Heo,

Affiliation Department of Bio-industrial Technologies, Konkuk University, Seoul, Republic of Korea
⨯
Yeondong Cho,

Affiliation Department of Bio-industrial Technologies, Konkuk University, Seoul, Republic of Korea
⨯
Yong-Dae Gwon,

Affiliation Department of Bio-industrial Technologies, Konkuk University, Seoul, Republic of Korea
⨯
Ki Hoon Park,

Affiliation Department of Bio-industrial Technologies, Konkuk University, Seoul, Republic of Korea
⨯
Hyerim Jin,

Affiliation College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea
⨯
Jinyoung Kim,

Affiliation College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea
⨯
Yu-Kyoung Oh ,

* E-mail: ohyk@snu.ac.kr (YKO); kimera@konkuk.ac.kr (YBK)

Affiliation College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea
⨯
Young Bong Kim

* E-mail: ohyk@snu.ac.kr (YKO); kimera@konkuk.ac.kr (YBK)

Affiliation Department of Bio-industrial Technologies, Konkuk University, Seoul, Republic of Korea
⨯

Sublingual Immunization of Trivalent Human Papillomavirus DNA Vaccine in Baculovirus Nanovector for Protection against Vaginal Challenge

Hee-Jung Lee,
Hansam Cho,
Mi-Gyeong Kim,
Yoon-Ki Heo,
Yeondong Cho,
Yong-Dae Gwon,
Ki Hoon Park,
Hyerim Jin,
Jinyoung Kim,
Yu-Kyoung Oh

Published: March 19, 2015
https://doi.org/10.1371/journal.pone.0119408

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