An ADAM33 Polymorphism Associates with Progression of Preschool Wheeze into Childhood Asthma: A Prospective Case-Control Study with Replication in a Birth Cohort Study

• Ester M. M. Klaassen ,

  * E-mail: ester.klaassen@mumc.nl

  Affiliation Department of Paediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands

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• John Penders,

  Affiliation Department of Epidemiology, CAPHRI, MUMC+, Maastricht, the Netherlands

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• Quirijn Jöbsis,

  Affiliation Department of Paediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands

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• Kim D. G. van de Kant,

  Affiliation Department of Paediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands

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• Carel Thijs,

  Affiliation Department of Epidemiology, CAPHRI, MUMC+, Maastricht, the Netherlands

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• Monique Mommers,

  Affiliation Department of Epidemiology, CAPHRI, MUMC+, Maastricht, the Netherlands

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• Constant P. van Schayck,

  Affiliation Department of General Practice, CAPHRI, MUMC+, Maastricht, the Netherlands

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• Guillaume van Eys,

  Affiliation Department of Genetics and Cell Biology, Cardiovascular Research Institute (CARIM), MUMC, Maastricht, the Netherlands

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• Gerard H. Koppelman,

  Affiliation Department of Paediatric Pulmonology and Paediatric Allergology, Beatrix Children’s Hospital, Groningen Research Institute for Asthma and COPD (GRIAC), University of Groningen, University Medical Centre Groningen, Groningen, the Netherlands

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• Edward Dompeling

  Affiliation Department of Paediatric Respiratory Medicine, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands

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