Disrupting Protein Expression with Peptide Nucleic Acids Reduces Infection by Obligate Intracellular Rickettsia

Rebecca S. Pelc; Jennifer C. McClure; Simran J. Kaur; Khandra T. Sears; M. Sayeedur Rahman; Shane M. Ceraul

doi:10.1371/journal.pone.0119283

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Peer-reviewed

Research Article

Disrupting Protein Expression with Peptide Nucleic Acids Reduces Infection by Obligate Intracellular Rickettsia

Rebecca S. Pelc,

Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Jennifer C. McClure,

Current address: Irish Cattle Breeders Federation Society Ltd., Highfield House, Shinagh, Bandon, Co Cork, Ireland

Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Simran J. Kaur,

Current address: Fischell Department of Bioengineering, University of Maryland, College Park, Maryland, United States of America

Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Khandra T. Sears,

Current address: Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, United States of America; USA Division of Infectious Diseases and Tropical Pediatrics, Department of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
M. Sayeedur Rahman,

Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯
Shane M. Ceraul

* E-mail: scera001@umaryland.edu

Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
⨯

Disrupting Protein Expression with Peptide Nucleic Acids Reduces Infection by Obligate Intracellular Rickettsia

Rebecca S. Pelc,
Jennifer C. McClure,
Simran J. Kaur,
Khandra T. Sears,
M. Sayeedur Rahman,
Shane M. Ceraul

Published: March 17, 2015
https://doi.org/10.1371/journal.pone.0119283

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Protein expression
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Rickettsia
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Protein synthesis
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Outer membrane proteins
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