Small Peptide Inhibitor of JNK3 Protects Dopaminergic Neurons from MPTP Induced Injury via Inhibiting the ASK1-JNK3 Signaling Pathway

Jing Pan; Hui Li; Bei Zhang; Ran Xiong; Yu Zhang; Wen-Yan Kang; Wei Chen; Zong-Bo Zhao; Sheng-Di Chen

doi:10.1371/journal.pone.0119204

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Peer-reviewed

Research Article

Small Peptide Inhibitor of JNK3 Protects Dopaminergic Neurons from MPTP Induced Injury via Inhibiting the ASK1-JNK3 Signaling Pathway

Jing Pan ,

¶‡ These authors contributed equally to this work as joint first authors.

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Hui Li ,

¶‡ These authors contributed equally to this work as joint first authors.

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Bei Zhang,

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Ran Xiong,

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Yu Zhang,

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Wen-Yan Kang,

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Wei Chen,

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Zong-Bo Zhao,

Affiliation Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Sheng-Di Chen

* E-mail: chen_sd@medmail.com.cn

Affiliations Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China, Key Laboratory of Stem Cell Biology & Laboratory of Neurodegenerative Diseases, Institute of Health Science, Shanghai Institutes of Biological Sciences (SIBS), Chinese Academy of Science (CAS) and Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯

Small Peptide Inhibitor of JNK3 Protects Dopaminergic Neurons from MPTP Induced Injury via Inhibiting the ASK1-JNK3 Signaling Pathway

Jing Pan,
Hui Li,
Bei Zhang,
Ran Xiong,
Yu Zhang,
Wen-Yan Kang,
Wei Chen,
Zong-Bo Zhao,
Sheng-Di Chen

Published: April 9, 2015
https://doi.org/10.1371/journal.pone.0119204

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