Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity

Maxime G. Blanchard; Jeroen H. F. de Baaij; Sjoerd A. J. Verkaart; Anke L. Lameris; Christine Basmadjian; Qian Zhao; Laurent Désaubry; René J. M. Bindels; Joost G. J. Hoenderop

doi:10.1371/journal.pone.0119028

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Open Access

Peer-reviewed

Research Article

Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity

Maxime G. Blanchard ,

Contributed equally to this work with: Maxime G. Blanchard, Jeroen H. F. de Baaij

Affiliation Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
⨯
Jeroen H. F. de Baaij ,

Contributed equally to this work with: Maxime G. Blanchard, Jeroen H. F. de Baaij

Affiliation Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
⨯
Sjoerd A. J. Verkaart,

Affiliation Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
⨯
Anke L. Lameris,

Affiliation Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
⨯
Christine Basmadjian,

Affiliation Laboratory of Therapeutic Innovation (UMR7200), CNRS-University of Strasbourg, Faculty of Pharmacy, Illkirch, France
⨯
Qian Zhao,

Affiliation Laboratory of Therapeutic Innovation (UMR7200), CNRS-University of Strasbourg, Faculty of Pharmacy, Illkirch, France
⨯
Laurent Désaubry,

Affiliation Laboratory of Therapeutic Innovation (UMR7200), CNRS-University of Strasbourg, Faculty of Pharmacy, Illkirch, France
⨯
René J. M. Bindels,

Affiliation Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
⨯
Joost G. J. Hoenderop

* E-mail: joost.hoenderop@radboudumc.nl

Affiliation Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands
⨯

Flavaglines Stimulate Transient Receptor Potential Melastatin Type 6 (TRPM6) Channel Activity

Maxime G. Blanchard,
Jeroen H. F. de Baaij,
Sjoerd A. J. Verkaart,
Anke L. Lameris,
Christine Basmadjian,
Qian Zhao,
Laurent Désaubry,
René J. M. Bindels,
Joost G. J. Hoenderop

Published: March 16, 2015
https://doi.org/10.1371/journal.pone.0119028

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