Metabolic Remodeling in Moderate Synchronous versus Dyssynchronous Pacing-Induced Heart Failure: Integrated Metabolomics and Proteomics Study

Junko Shibayama; Tatiana N. Yuzyuk; James Cox; Aman Makaju; Mickey Miller; Justin Lichter; Hui Li; Jane D. Leavy; Sarah Franklin; Alexey V. Zaitsev

doi:10.1371/journal.pone.0118974

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Peer-reviewed

Research Article

Metabolic Remodeling in Moderate Synchronous versus Dyssynchronous Pacing-Induced Heart Failure: Integrated Metabolomics and Proteomics Study

Junko Shibayama,

Affiliations Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of America, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
⨯
Tatiana N. Yuzyuk,

Affiliations Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, ARUP Laboratories, Salt Lake City, Utah, United States of America
⨯
James Cox,

Affiliations Metabolomics Core Research Facility, University of Utah, Salt Lake City, Utah, United States of America, Department of Biochemistry, University of Utah, Salt Lake City, Utah, United States of America
⨯
Aman Makaju,

Affiliation Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of America
⨯
Mickey Miller,

Affiliation Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of America
⨯
Justin Lichter,

Affiliations Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of America, Department of Bioengineering, University of Utah, Salt Lake City, Utah, United States of America
⨯
Hui Li,

Affiliation Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of America
⨯
Jane D. Leavy,

Affiliation Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
⨯
Sarah Franklin,

Affiliations Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of America, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, United States of America, Department of Biochemistry, University of Utah, Salt Lake City, Utah, United States of America
⨯
Alexey V. Zaitsev

* E-mail: zaitsev@cvrti.utah.edu

Affiliations Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, Utah, United States of America, Department of Bioengineering, University of Utah, Salt Lake City, Utah, United States of America
⨯

Metabolic Remodeling in Moderate Synchronous versus Dyssynchronous Pacing-Induced Heart Failure: Integrated Metabolomics and Proteomics Study

Junko Shibayama,
Tatiana N. Yuzyuk,
James Cox,
Aman Makaju,
Mickey Miller,
Justin Lichter,
Hui Li,
Jane D. Leavy,
Sarah Franklin,
Alexey V. Zaitsev

Published: March 19, 2015
https://doi.org/10.1371/journal.pone.0118974

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Creatine
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