Microbiota-Independent Ameliorative Effects of Antibiotics on Spontaneous Th2-Associated Pathology of the Small Intestine

Daehee Han; Matthew C. Walsh; Kwang Soon Kim; Sung-Wook Hong; Junyoung Lee; Jaeu Yi; Gloriany Rivas; Charles D. Surh; Yongwon Choi

doi:10.1371/journal.pone.0118795

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Open Access

Peer-reviewed

Research Article

Microbiota-Independent Ameliorative Effects of Antibiotics on Spontaneous Th2-Associated Pathology of the Small Intestine

Daehee Han,

Affiliations Academy of Immunology and Microbiology, Institute for Basic Science, Pohang, 790–784, Republic of Korea, Department of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790–784, Republic of Korea
⨯
Matthew C. Walsh,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, 19104, United States of America
⨯
Kwang Soon Kim,

Affiliations Academy of Immunology and Microbiology, Institute for Basic Science, Pohang, 790–784, Republic of Korea, Department of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790–784, Republic of Korea
⨯
Sung-Wook Hong,

Affiliations Academy of Immunology and Microbiology, Institute for Basic Science, Pohang, 790–784, Republic of Korea, Department of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790–784, Republic of Korea
⨯
Junyoung Lee,

Affiliations Academy of Immunology and Microbiology, Institute for Basic Science, Pohang, 790–784, Republic of Korea, Department of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790–784, Republic of Korea
⨯
Jaeu Yi,

Affiliations Academy of Immunology and Microbiology, Institute for Basic Science, Pohang, 790–784, Republic of Korea, Department of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790–784, Republic of Korea
⨯
Gloriany Rivas,

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, 19104, United States of America
⨯
Charles D. Surh ,

* E-mail: ychoi3@mail.med.upenn.edu (YC); csurh@ibs.re.kr (CDS)

Affiliations Academy of Immunology and Microbiology, Institute for Basic Science, Pohang, 790–784, Republic of Korea, Department of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, Pohang, 790–784, Republic of Korea, Division of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California, 92037, United States of America
⨯
Yongwon Choi

* E-mail: ychoi3@mail.med.upenn.edu (YC); csurh@ibs.re.kr (CDS)

Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, 19104, United States of America
⨯

Microbiota-Independent Ameliorative Effects of Antibiotics on Spontaneous Th2-Associated Pathology of the Small Intestine

Daehee Han,
Matthew C. Walsh,
Kwang Soon Kim,
Sung-Wook Hong,
Junyoung Lee,
Jaeu Yi,
Gloriany Rivas,
Charles D. Surh,
Yongwon Choi

Published: February 17, 2015
https://doi.org/10.1371/journal.pone.0118795

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