Co-Infection with Mycobacterium tuberculosis Impairs HIV-Specific CD8+ and CD4+ T Cell Functionality

• Shivan Chetty,

  Affiliations HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa, KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), University of KwaZulu-Natal, Durban, South Africa

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• Pamla Govender,

  Affiliation HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa

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• Jennifer Zupkosky,

  Affiliation The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Mona Pillay,

  Affiliation HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa

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• Musie Ghebremichael,

  Affiliation The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Mahomed-Yunus S. Moosa,

  Affiliation Department of Infectious Disease, Division of Internal Medicine, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa

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• Thumbi Ndung’u,

  Affiliations HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa, KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), University of KwaZulu-Natal, Durban, South Africa, The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America, Max Planck Institute for Infection Biology, Berlin, Germany

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• Filippos Porichis ,

  Contributed equally to this work with: Filippos Porichis, Victoria O. Kasprowicz

  Affiliation The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

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• Victoria O. Kasprowicz

  Contributed equally to this work with: Filippos Porichis, Victoria O. Kasprowicz

  * E-mail: vkasprowicz@mgh.harvard.edu

  Affiliations HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa, KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), University of KwaZulu-Natal, Durban, South Africa, The Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, United States of America

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