A Computer-Assisted 3D Model for Analyzing the Aggregation of Tumorigenic Cells Reveals Specialized Behaviors and Unique Cell Types that Facilitate Aggregate Coalescence

Amanda Scherer; Spencer Kuhl; Deborah Wessels; Daniel F. Lusche; Brett Hanson; Joseph Ambrose; Edward Voss; Emily Fletcher; Charles Goldman; David R. Soll

doi:10.1371/journal.pone.0118628

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Research Article

A Computer-Assisted 3D Model for Analyzing the Aggregation of Tumorigenic Cells Reveals Specialized Behaviors and Unique Cell Types that Facilitate Aggregate Coalescence

Amanda Scherer,

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯
Spencer Kuhl,

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯
Deborah Wessels,

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯
Daniel F. Lusche,

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯
Brett Hanson,

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯
Joseph Ambrose,

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯
Edward Voss,

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯
Emily Fletcher,

Affiliation Mercy Hospital System of Des Moines, Des Moines, Iowa, United States of America
⨯
Charles Goldman,

Affiliation Mercy Hospital System of Des Moines, Des Moines, Iowa, United States of America
⨯
David R. Soll

* E-mail: david-soll@uiowa.edu

Affiliation Monoclonal Antibody Research Institute, Developmental Studies Hybridoma Bank, Department of Biology, University of Iowa, Iowa City, Iowa, 52242, United States of America
⨯

A Computer-Assisted 3D Model for Analyzing the Aggregation of Tumorigenic Cells Reveals Specialized Behaviors and Unique Cell Types that Facilitate Aggregate Coalescence

Amanda Scherer,
Spencer Kuhl,
Deborah Wessels,
Daniel F. Lusche,
Brett Hanson,
Joseph Ambrose,
Edward Voss,
Emily Fletcher,
Charles Goldman,
David R. Soll

Published: March 19, 2015
https://doi.org/10.1371/journal.pone.0118628

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