Overexpression of the Transcription Factor Sp1 Activates the OAS-RNAse L-RIG-I Pathway

Valéryane Dupuis-Maurin; Lilia Brinza; Joël Baguet; Emilie Plantamura; Stéphane Schicklin; Solène Chambion; Claire Macari; Martine Tomkowiak; Emmanuelle Deniaud; Yann Leverrier; Jacqueline Marvel; Marie-Cécile Michallet

doi:10.1371/journal.pone.0118551

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Open Access

Peer-reviewed

Research Article

Overexpression of the Transcription Factor Sp1 Activates the OAS-RNAse L-RIG-I Pathway

Valéryane Dupuis-Maurin,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Lilia Brinza,

Current address: PT Génomique et Transcriptomique, BIOASTER, Lyon, France.

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Joël Baguet,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Emilie Plantamura,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Stéphane Schicklin,

Current address: Biomérieux, Marcy-l’Etoile, France.

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Solène Chambion,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Claire Macari,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Martine Tomkowiak,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Emmanuelle Deniaud,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Yann Leverrier,

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Jacqueline Marvel ,

Contributed equally to this work with: Jacqueline Marvel, Marie-Cécile Michallet

* E-mail: jacqueline.marvel@inserm.fr (JM); marie-cecile.michallet@inserm.fr (MCM)

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯
Marie-Cécile Michallet

Contributed equally to this work with: Jacqueline Marvel, Marie-Cécile Michallet

* E-mail: jacqueline.marvel@inserm.fr (JM); marie-cecile.michallet@inserm.fr (MCM)

Current address: Cancer Research Center Lyon (CRCL), UMR INSERM 1052 CNRS 5286, Centre Leon Berard, Lyon, France.

Affiliation Centre International de Recherche en Infectiologie, INSERM U111-CNRS UMR5308, Université de Lyon 1, ENS de Lyon, Lyon, France
⨯

Overexpression of the Transcription Factor Sp1 Activates the OAS-RNAse L-RIG-I Pathway

Valéryane Dupuis-Maurin,
Lilia Brinza,
Joël Baguet,
Emilie Plantamura,
Stéphane Schicklin,
Solène Chambion,
Claire Macari,
Martine Tomkowiak,
Emmanuelle Deniaud,
Yann Leverrier

Published: March 4, 2015
https://doi.org/10.1371/journal.pone.0118551

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DNA damage
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Transcription factors
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