shRNA Off-Target Effects In Vivo: Impaired Endogenous siRNA Expression and Spermatogenic Defects

• Hye-Won Song,

  Affiliation Department of Reproductive Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Anilkumar Bettegowda,

  Affiliation Department of Reproductive Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Daniel Oliver,

  Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

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• Wei Yan,

  Affiliation Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada, United States of America

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• Mimi H. Phan,

  Affiliation Department of Reproductive Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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• Dirk G. de Rooij,

  Affiliation Center for Reproductive Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Mark A. Corbett,

  Affiliation School of Pediatrics and Reproductive Health, The University of Adelaide, Adelaide, Australia

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• Miles F. Wilkinson

  * E-mail: mfwilkinson@ucsd.edu

  Affiliation Department of Reproductive Medicine, School of Medicine, University of California San Diego, La Jolla, California, United States of America

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