Reciprocal Interaction of Wnt and RXR-α Pathways in Hepatocyte Development and Hepatocellular Carcinoma

Jinyu Li; Maia Chanrion; Eric Sawey; Tim Wang; Edward Chow; Aaron Tward; Yi Su; Wen Xue; Robert Lucito; Lars Zender; Scott W. Lowe; J. Michael Bishop; Scott Powers

doi:10.1371/journal.pone.0118480

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Open Access

Peer-reviewed

Research Article

Reciprocal Interaction of Wnt and RXR-α Pathways in Hepatocyte Development and Hepatocellular Carcinoma

Jinyu Li ,

Contributed equally to this work with: Jinyu Li, Maia Chanrion

Affiliation Cancer Genome Center, Cold Spring Harbor Laboratory, Woodbury, NY 11740, United States of America
⨯
Maia Chanrion ,

Contributed equally to this work with: Jinyu Li, Maia Chanrion

Affiliation Cancer Genome Center, Cold Spring Harbor Laboratory, Woodbury, NY 11740, United States of America
⨯
Eric Sawey,

Affiliation Cancer Genome Center, Cold Spring Harbor Laboratory, Woodbury, NY 11740, United States of America
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Tim Wang,

Affiliation Cancer Genome Center, Cold Spring Harbor Laboratory, Woodbury, NY 11740, United States of America
⨯
Edward Chow,

Affiliation Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599, Singapore
⨯
Aaron Tward,

Affiliation G. W. Hooper Foundation and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143, United States of America
⨯
Yi Su,

Affiliation Cancer Genome Center, Cold Spring Harbor Laboratory, Woodbury, NY 11740, United States of America
⨯
Wen Xue,

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, United States of America
⨯
Robert Lucito,

Affiliation Cancer Genome Center, Cold Spring Harbor Laboratory, Woodbury, NY 11740, United States of America
⨯
Lars Zender,

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, United States of America
⨯
Scott W. Lowe,

Affiliation Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, United States of America
⨯
J. Michael Bishop,

Affiliation G. W. Hooper Foundation and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143, United States of America
⨯
Scott Powers

* E-mail: rscottpowers@gmail.com

Affiliations Cancer Genome Center, Cold Spring Harbor Laboratory, Woodbury, NY 11740, United States of America, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, United States of America
⨯

Reciprocal Interaction of Wnt and RXR-α Pathways in Hepatocyte Development and Hepatocellular Carcinoma

Jinyu Li,
Maia Chanrion,
Eric Sawey,
Tim Wang,
Edward Chow,
Aaron Tward,
Yi Su,
Wen Xue,
Robert Lucito,
Lars Zender

Published: March 4, 2015
https://doi.org/10.1371/journal.pone.0118480

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Wnt signaling cascade
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