A Rapid Molecular Approach for Chromosomal Phasing

John F. Regan; Nolan Kamitaki; Tina Legler; Samantha Cooper; Niels Klitgord; George Karlin-Neumann; Catherine Wong; Shawn Hodges; Ryan Koehler; Svilen Tzonev; Steven A. McCarroll

doi:10.1371/journal.pone.0118270

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Open Access

Peer-reviewed

Research Article

A Rapid Molecular Approach for Chromosomal Phasing

John F. Regan ,

Contributed equally to this work with: John F. Regan, Nolan Kamitaki

* E-mail: jack_regan@bio-rad.com (JFR); mccarroll@genetics.med.harvard.edu (SAM)

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
Nolan Kamitaki ,

Contributed equally to this work with: John F. Regan, Nolan Kamitaki

Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Cambridge, Massachusetts, United States of America
⨯
Tina Legler,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
Samantha Cooper,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
Niels Klitgord,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
George Karlin-Neumann,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
Catherine Wong,

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Shawn Hodges,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
Ryan Koehler,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
Svilen Tzonev,

Affiliation Digital Biology Center, Bio-Rad Laboratories, Pleasanton, California, United States of America
⨯
Steven A. McCarroll

* E-mail: jack_regan@bio-rad.com (JFR); mccarroll@genetics.med.harvard.edu (SAM)

Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics and Stanley Center for Psychiatric Research, Cambridge, Massachusetts, United States of America
⨯

A Rapid Molecular Approach for Chromosomal Phasing

John F. Regan,
Nolan Kamitaki,
Tina Legler,
Samantha Cooper,
Niels Klitgord,
George Karlin-Neumann,
Catherine Wong,
Shawn Hodges,
Ryan Koehler,
Svilen Tzonev

Published: March 4, 2015
https://doi.org/10.1371/journal.pone.0118270

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Genomics
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Haplotypes
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Genome analysis
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Heterozygosity
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Alleles
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DNA extraction
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Single nucleotide polymorphisms
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Polymerase chain reaction
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