Vasoactivity of Rucaparib, a PARP-1 Inhibitor, is a Complex Process that Involves Myosin Light Chain Kinase, P2 Receptors, and PARP Itself

• Cian M. McCrudden ,

  * E-mail: c.mccrudden@qub.ac.uk

  Affiliation School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom

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• Martin G. O’Rourke,

  Affiliation School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom

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• Kim E. Cherry,

  Affiliation School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom

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• Hiu-Fung Yuen,

  Affiliation Centre for Cancer Research and Cell Biology, Queen’s University Belfast, Belfast, United Kingdom

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• Declan O’Rourke,

  Affiliation Belfast Health and Social Care Trust, Belfast, United Kingdom

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• Muhammad Babur,

  Affiliation Manchester Pharmacy School, The University of Manchester, Manchester, United Kingdom

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• Brian A. Telfer,

  Affiliation Manchester Pharmacy School, The University of Manchester, Manchester, United Kingdom

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• Huw D. Thomas,

  Affiliation Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom

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• Patrick Keane,

  Affiliation Belfast Health and Social Care Trust, Belfast, United Kingdom

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• Thiagarajan Nambirajan,

  Affiliation Belfast Health and Social Care Trust, Belfast, United Kingdom

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• Chris Hagan,

  Affiliation Belfast Health and Social Care Trust, Belfast, United Kingdom

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• Joe M. O’Sullivan,

  Affiliations Centre for Cancer Research and Cell Biology, Queen’s University Belfast, Belfast, United Kingdom, Belfast Health and Social Care Trust, Belfast, United Kingdom

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• Chris Shaw,

  Affiliation School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom

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• Kaye J. Williams,

  Affiliation Manchester Pharmacy School, The University of Manchester, Manchester, United Kingdom

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• Nicola J. Curtin,

  Affiliation Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom

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• David G. Hirst,

  Affiliation School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom

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•  [ ... ],
• Tracy Robson

  Affiliation School of Pharmacy, Queen’s University Belfast, Belfast, United Kingdom

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