The Rotary Zone Thermal Cycler: A Low-Power System Enabling Automated Rapid PCR

Michael S. Bartsch; Harrison S. Edwards; Daniel Lee; Caroline E. Moseley; Karen E. Tew; Ronald F. Renzi; James  L. Van de Vreugde; Hanyoup Kim; Daniel L. Knight; Anupama Sinha; Steven S. Branda; Kamlesh D. Patel

doi:10.1371/journal.pone.0118182

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Open Access

Peer-reviewed

Research Article

The Rotary Zone Thermal Cycler: A Low-Power System Enabling Automated Rapid PCR

Michael S. Bartsch ,

* E-mail: mbarts@sandia.gov

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Harrison S. Edwards ,

Contributed equally to this work with: Harrison S. Edwards, Daniel Lee, Caroline E. Moseley, Karen E. Tew

Current address: Gas Transmission Systems, Walnut Creek, CA, United States of America

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Daniel Lee ,

Contributed equally to this work with: Harrison S. Edwards, Daniel Lee, Caroline E. Moseley, Karen E. Tew

Current address: Abiocode, Agoura Hills, CA, United States of America

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Caroline E. Moseley ,

Contributed equally to this work with: Harrison S. Edwards, Daniel Lee, Caroline E. Moseley, Karen E. Tew

Current address: Georgetown University, Washington, D.C., United States of America

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Karen E. Tew ,

Contributed equally to this work with: Harrison S. Edwards, Daniel Lee, Caroline E. Moseley, Karen E. Tew

Current address: Utah State University, Logan, UT, United States of America

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Ronald F. Renzi,

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
James L. Van de Vreugde,

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Hanyoup Kim,

Current address: Canon U.S. Life Sciences, Rockville, MD, United States of America

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Daniel L. Knight,

Affiliation SequoiaTek Corporation, Logan, UT, United States of America
⨯
Anupama Sinha,

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Steven S. Branda,

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯
Kamlesh D. Patel

Affiliation Sandia National Laboratories, Livermore, CA, United States of America
⨯

The Rotary Zone Thermal Cycler: A Low-Power System Enabling Automated Rapid PCR

Michael S. Bartsch,
Harrison S. Edwards,
Daniel Lee,
Caroline E. Moseley,
Karen E. Tew,
Ronald F. Renzi,
James L. Van de Vreugde,
Hanyoup Kim,
Daniel L. Knight,
Anupama Sinha

Published: March 31, 2015
https://doi.org/10.1371/journal.pone.0118182

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Polymerase chain reaction
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Microfluidics
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Thermal conductivity
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cDNA synthesis
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