Heat Stress-Induced Disruption of Endothelial Barrier Function Is via PAR1 Signaling and Suppressed by Xuebijing Injection

Open Access

Peer-reviewed

Research Article

Qiulin Xu ,

¶‡ These authors contributed equally to this work.

Affiliations Department of ICU, General Hospital of Guangzhou Military Command, Key Laboratory of Tropical Zone Trauma Care and Tissue Repair of PLA, Guangzhou, China, Postdoctoral Workstation, Huabo Bio-pharmaceutical Research Institute, Guangzhou, China
⨯
Jingxian Liu ,

¶‡ These authors contributed equally to this work.

Affiliation Southern Medical University, Guangzhou, China
⨯
Zhenglian Wang,

Affiliation Guangzhou University of Chinese Medicine, Guangzhou, China
⨯
Xiaohua Guo,

Affiliation Department of Pathophysiology, Southern Medical University, Guangzhou, China
⨯
Gengbiao Zhou,

Affiliation Guangzhou University of Chinese Medicine, Guangzhou, China
⨯
Yanan Liu,

Affiliation Southern Medical University, Guangzhou, China
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Qiaobing Huang ,

* E-mail: bing@smu.edu.cn (QH); slei_icu@163.com (LS)

Affiliation Department of Pathophysiology, Southern Medical University, Guangzhou, China
⨯
Lei Su

* E-mail: bing@smu.edu.cn (QH); slei_icu@163.com (LS)

Affiliation Department of ICU, General Hospital of Guangzhou Military Command, Key Laboratory of Tropical Zone Trauma Care and Tissue Repair of PLA, Guangzhou, China
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Hyperthermia
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Thermal stresses
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Phosphorylation
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Small interfering RNA
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Protein expression
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Endothelial cells
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Vascular permeability
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Permeability
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