A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival

Eva J. A. Morris; Steve Penegar; Nicola Whiffin; Peter Broderick; D. Timothy Bishop; Emma Northwood; Philip Quirke; Paul Finan; Richard S. Houlston

doi:10.1371/journal.pone.0117816

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Open Access

Peer-reviewed

Research Article

A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival

Eva J. A. Morris ,

* E-mail: e.morris@leeds.ac.uk

Affiliation Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds LS9 7TF, United Kingdom
⨯
Steve Penegar,

Affiliation Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, United Kingdom
⨯
Nicola Whiffin,

Affiliation Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, United Kingdom
⨯
Peter Broderick,

Affiliation Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, United Kingdom
⨯
D. Timothy Bishop,

Affiliation Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds LS9 7TF, United Kingdom
⨯
Emma Northwood,

Affiliation Section of Epidemiology and Biostatistics, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds LS9 7TF, United Kingdom
⨯
Philip Quirke,

Affiliation Pathology and Tumour Biology, Leeds Institute of Cancer and Pathology, Level 4 Wellcome Trust Brenner Building, St James’s University Hospital, Leeds LS9 7TF, United Kingdom
⨯
Paul Finan,

Affiliations John Goligher Colorectal Unit, Leeds Teaching Hospitals, St James’s University Hospital, Beckett Street, Leeds, LS9 7TF, United Kingdom, National Cancer Intelligence Network, 18th Floor Portland House, Bressenden Place, London, SW1E 5RS, United Kingdom
⨯
Richard S. Houlston

Affiliation Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, SM2 5NG, United Kingdom
⨯

A Retrospective Observational Study of the Relationship between Single Nucleotide Polymorphisms Associated with the Risk of Developing Colorectal Cancer and Survival

Eva J. A. Morris,
Steve Penegar,
Nicola Whiffin,
Peter Broderick,
D. Timothy Bishop,
Emma Northwood,
Philip Quirke,
Paul Finan,
Richard S. Houlston

Published: February 24, 2015
https://doi.org/10.1371/journal.pone.0117816

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Colorectal cancer
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Single nucleotide polymorphisms
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Cancer risk factors
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Prognosis
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Genome-wide association studies
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Cancer detection and diagnosis
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Human genetics
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Variant genotypes
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