In Vitro and In Vivo Antitumor Activity of a Novel Semisynthetic Derivative of Cucurbitacin B

• Izabella T. Silva,

  Affiliations Department of Pharmaceutical Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil, Institute of Molecular Virology (IMV), Center of Molecular Biology of Inflammation (ZMBE), Westfaelische-Wilhelms-University, Muenster, Germany

  ⨯
• Annelise Carvalho,

  Affiliation Department of Pharmaceutical Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil

  ⨯
• Karen L. Lang,

  Affiliation Department of Chemistry, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil

  ⨯
• Sabine E. Dudek,

  Affiliation Institute of Molecular Virology (IMV), Center of Molecular Biology of Inflammation (ZMBE), Westfaelische-Wilhelms-University, Muenster, Germany

  ⨯
• Dörthe Masemann,

  Affiliation Institute of Molecular Virology (IMV), Center of Molecular Biology of Inflammation (ZMBE), Westfaelische-Wilhelms-University, Muenster, Germany

  ⨯
• Fernando J. Durán,

  Affiliation UMYMFOR, Department of Organic Chemistry, Universidad de Buenos Aires, Buenos Aires, Argentina

  ⨯
• Miguel S. B. Caro,

  Affiliation Department of Chemistry, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil

  ⨯
• Ulf R. Rapp,

  Affiliation Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany

  ⨯
• Viktor Wixler,

  Affiliations Institute of Molecular Virology (IMV), Center of Molecular Biology of Inflammation (ZMBE), Westfaelische-Wilhelms-University, Muenster, Germany, Cells in Motion, Cluster of Excellence, Westfaelische-Wilhelms-University, Muenster, Germany

  ⨯
• Eloir P. Schenkel,

  Affiliation Department of Pharmaceutical Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil

  ⨯
• Cláudia M. O. Simões,

  Affiliation Department of Pharmaceutical Sciences, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil

  ⨯
• Stephan Ludwig

  * E-mail: ludwigs@uni-muenster.de

  Affiliations Institute of Molecular Virology (IMV), Center of Molecular Biology of Inflammation (ZMBE), Westfaelische-Wilhelms-University, Muenster, Germany, Cells in Motion, Cluster of Excellence, Westfaelische-Wilhelms-University, Muenster, Germany, Interdisciplinary Center of Clinical Research (IZKF), Westfaelische-Wilhelms-University, Muenster, Germany

  ⨯