Data-Driven Asthma Endotypes Defined from Blood Biomarker and Gene Expression Data

• Barbara Jane George ,

  ¶‡ These authors contributed equally to this work.

  Affiliation National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• David M. Reif ,

  Current address: Biological Sciences Department, North Carolina State University, Raleigh, North Carolina, United States of America

  ¶‡ These authors contributed equally to this work.

  Affiliation National Center for Computational Toxicology, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• Jane E. Gallagher,

  Affiliation National Health and Environmental Effects Research Laboratory—Environmental Public Health Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• ClarLynda R. Williams-DeVane,

  Current address: Biology Department, North Carolina Central University, Durham, North Carolina, United States of America

  Affiliation National Health and Environmental Effects Research Laboratory—Integrated Systems Toxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• Brooke L. Heidenfelder,

  Current address: Duke Translational Medicine Institute, Duke University, Durham, North Carolina, United States of America

  Affiliation National Health and Environmental Effects Research Laboratory—Environmental Public Health Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• Edward E. Hudgens,

  Affiliation National Health and Environmental Effects Research Laboratory—Environmental Public Health Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• Wendell Jones,

  Affiliation Department of Bioinformatics, Expression Analysis, a Quintiles company, Durham, North Carolina, United States of America

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• Lucas Neas,

  Affiliation National Health and Environmental Effects Research Laboratory—Environmental Public Health Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• Elaine A. Cohen Hubal,

  Affiliation Office of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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• Stephen W. Edwards

  * E-mail: edwards.stephen@epa.gov

  Affiliation National Health and Environmental Effects Research Laboratory—Integrated Systems Toxicology Division, U.S. Environmental Protection Agency, Research Triangle Park, North Carolina, United States of America

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