Flow Increase Is Decisive to Initiate Angiogenesis in Veins Exposed to Altered Hemodynamics

Volker J. Schmidt; Johannes G. Hilgert; Jennifer M. Covi; Nico Leibig; Johanna O. Wietbrock; Andreas Arkudas; Elias Polykandriotis; Cor de Wit; Raymund E. Horch; Ulrich Kneser

doi:10.1371/journal.pone.0117407

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Open Access

Peer-reviewed

Research Article

Flow Increase Is Decisive to Initiate Angiogenesis in Veins Exposed to Altered Hemodynamics

Volker J. Schmidt ,

* E-mail: schmidtvolker@gmx.net

Affiliations Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, Department for Hand-, Plastic- and Reconstructive Surgery, BG Unfallklinik Ludwigshafen, Universität Heidelberg, Heidelberg, Germany
⨯
Johannes G. Hilgert,

Affiliation Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Jennifer M. Covi,

Affiliation Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Nico Leibig,

Affiliation Department for Hand-, Plastic- and Reconstructive Surgery, BG Unfallklinik Ludwigshafen, Universität Heidelberg, Heidelberg, Germany
⨯
Johanna O. Wietbrock,

Affiliation Department for Hand-, Plastic- and Reconstructive Surgery, BG Unfallklinik Ludwigshafen, Universität Heidelberg, Heidelberg, Germany
⨯
Andreas Arkudas,

Affiliation Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Elias Polykandriotis,

Affiliation Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Cor de Wit,

Affiliation Department for Physiology, Universität zu Lübeck, Lübeck, Germany
⨯
Raymund E. Horch,

Affiliation Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Ulrich Kneser

Affiliations Department of Plastic and Hand Surgery, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, Department for Hand-, Plastic- and Reconstructive Surgery, BG Unfallklinik Ludwigshafen, Universität Heidelberg, Heidelberg, Germany
⨯

Flow Increase Is Decisive to Initiate Angiogenesis in Veins Exposed to Altered Hemodynamics

Volker J. Schmidt,
Johannes G. Hilgert,
Jennifer M. Covi,
Nico Leibig,
Johanna O. Wietbrock,
Andreas Arkudas,
Elias Polykandriotis,
Cor de Wit,
Raymund E. Horch,
Ulrich Kneser

Published: January 30, 2015
https://doi.org/10.1371/journal.pone.0117407

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Veins
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Blood flow
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Angiogenesis
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Hemodynamics
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