Directed Evolution of a Yeast-Displayed HIV-1 SOSIP gp140 Spike Protein toward Improved Expression and Affinity for Conformational Antibodies

Open Access

Peer-reviewed

Research Article

Sebastian K. Grimm,

Affiliation Thayer School of Engineering at Dartmouth, Hanover, New Hampshire, United States of America
⨯
Michael B. Battles,

Affiliation Thayer School of Engineering at Dartmouth, Hanover, New Hampshire, United States of America
⨯
Margaret E. Ackerman

* E-mail: margaret.e.ackerman@dartmouth.edu

Affiliation Thayer School of Engineering at Dartmouth, Hanover, New Hampshire, United States of America
⨯

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Saccharomyces cerevisiae
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Yeast
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HIV
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Antibodies
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Binding analysis
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Cloning
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Antigens
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Pichia pastoris
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