Ghrelin Inhibits the Differentiation of T Helper 17 Cells through mTOR/STAT3 Signaling Pathway

Yanhui Xu; Ziru Li; Yue Yin; He Lan; Jun Wang; Jing Zhao; Juan Feng; Yin Li; Weizhen Zhang

doi:10.1371/journal.pone.0117081

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Open Access

Peer-reviewed

Research Article

Ghrelin Inhibits the Differentiation of T Helper 17 Cells through mTOR/STAT3 Signaling Pathway

Yanhui Xu,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
Ziru Li,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
Yue Yin,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
He Lan,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
Jun Wang,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
Jing Zhao,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
Juan Feng,

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
Yin Li ,

* E-mail: yinli@bjmu.edu.cn

Affiliation Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China
⨯
Weizhen Zhang

Affiliations Department of Physiology and Pathophysiology, Peking University Health Science Center, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China, Department of Surgery, University of Michigan, Ann Arbor, MI, United States of America
⨯

Ghrelin Inhibits the Differentiation of T Helper 17 Cells through mTOR/STAT3 Signaling Pathway

Yanhui Xu,
Ziru Li,
Yue Yin,
He Lan,
Jun Wang,
Jing Zhao,
Juan Feng,
Yin Li,
Weizhen Zhang

Published: February 6, 2015
https://doi.org/10.1371/journal.pone.0117081

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Cell differentiation
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STAT signaling
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