Cathepsin Inhibition-Induced Lysosomal Dysfunction Enhances Pancreatic Beta-Cell Apoptosis in High Glucose

Open Access

Peer-reviewed

Research Article

Minjeong Jung,

Affiliation Department of Brain Science, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Korea
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Jaemeun Lee,

Affiliation Department of Brain Science, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Korea
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Hye-Young Seo,

Affiliation Department of Brain Science, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Korea
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Ji Sun Lim,

Affiliation Department of Brain Science, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Korea
⨯
Eun-Kyoung Kim

* E-mail: ekkim@dgist.ac.kr

Affiliations Department of Brain Science, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Korea, Neurometabolomics Research Center, Daegu Gyeongbuk Institute of Science & Technology, Daegu, Korea
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Lysosomes
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Glucose
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Apoptosis
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Autophagic cell death
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Protease inhibitor therapy
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Proteases
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Cysteine
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Cell staining
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