Anti-Human α-Synuclein N-Terminal Peptide Antibody Protects against Dopaminergic Cell Death and Ameliorates Behavioral Deficits in an AAV-α-Synuclein Rat Model of Parkinson’s Disease

• Md Shahaduzzaman,

  Affiliation Center of Excellence for Aging & Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, Florida, 33612, United States of America

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• Kevin Nash,

  Affiliations Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida, 33612, United States of America, USF-Health Byrd Alzheimer’s Institute University of South Florida, Tampa, Florida, 33612, United States of America

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• Charles Hudson,

  Affiliation James A. Haley Veterans Affairs Hospital, Research Service, Tampa, Florida, 33612, United States of America

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• Masroor Sharif,

  Affiliation Center of Excellence for Aging & Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, Florida, 33612, United States of America

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• Bethany Grimmig,

  Affiliation Center of Excellence for Aging & Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, Florida, 33612, United States of America

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• Xiaoyang Lin,

  Affiliation USF-Health Byrd Alzheimer’s Institute University of South Florida, Tampa, Florida, 33612, United States of America

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• Ge Bai,

  Affiliation USF-Health Byrd Alzheimer’s Institute University of South Florida, Tampa, Florida, 33612, United States of America

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• Hui Liu,

  Affiliation USF-Health Byrd Alzheimer’s Institute University of South Florida, Tampa, Florida, 33612, United States of America

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• Kenneth E. Ugen,

  Affiliations Dept. of Molecular Medicine, University of South Florida Morsani College of Medicine, Tampa, Florida, 33612, United States of America, Center for Molecular Delivery, University of South Florida, Tampa, Florida, 33620, United States of America

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• Chuanhai Cao ,

  * E-mail: pbickfor@health.usf.edu (PB); ccao@health.usf.edu (CC)

  Affiliations USF-Health Byrd Alzheimer’s Institute University of South Florida, Tampa, Florida, 33612, United States of America, Dept. of Pharmaceutical Sciences, College of Pharmacy, University of South Florida, Tampa, Florida, 33612, United States of America

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• Paula C. Bickford

  * E-mail: pbickfor@health.usf.edu (PB); ccao@health.usf.edu (CC)

  Affiliations Center of Excellence for Aging & Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida Morsani College of Medicine, Tampa, Florida, 33612, United States of America, Molecular Pharmacology and Physiology, University of South Florida Morsani College of Medicine, Tampa, Florida, 33612, United States of America, James A. Haley Veterans Affairs Hospital, Research Service, Tampa, Florida, 33612, United States of America

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