The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death

Jia-Dong Fan; Pin-Ji Lei; Jun-Yi Zheng; Xiang Wang; Shangze Li; Huan Liu; Yi-Lei He; Zhao-Ning Wang; Gang Wei; Xiaodong Zhang; Lian-Yun Li; Min Wu

doi:10.1371/journal.pone.0116782

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Open Access

Peer-reviewed

Research Article

The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death

Jia-Dong Fan,

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Pin-Ji Lei,

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Jun-Yi Zheng,

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Xiang Wang,

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Shangze Li,

Affiliation Department of Cell Biology and Development Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Huan Liu,

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Yi-Lei He,

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Zhao-Ning Wang,

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Gang Wei,

Affiliation CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China
⨯
Xiaodong Zhang,

Affiliation Department of Cell Biology and Development Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Lian-Yun Li ,

* E-mail: wumin@whu.edu.cn (MW); lilianyun@whu.edu.cn (LYL)

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯
Min Wu

* E-mail: wumin@whu.edu.cn (MW); lilianyun@whu.edu.cn (LYL)

Affiliation Department of Biochemistry and Molecular Biology, College of Life Sciences, Wuhan University, Wuhan, Hubei 430072, China
⨯

The Selective Activation of p53 Target Genes Regulated by SMYD2 in BIX-01294 Induced Autophagy-Related Cell Death

Jia-Dong Fan,
Pin-Ji Lei,
Jun-Yi Zheng,
Xiang Wang,
Shangze Li,
Huan Liu,
Yi-Lei He,
Zhao-Ning Wang,
Gang Wei,
Xiaodong Zhang

Published: January 6, 2015
https://doi.org/10.1371/journal.pone.0116782

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Autophagic cell death
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Gene expression
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Apoptosis
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Small interfering RNA
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Gene regulation
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