Crucial Role of IL1beta and C3a in the In Vitro-Response of Multipotent Mesenchymal Stromal Cells to Inflammatory Mediators of Polytrauma

Open Access

Peer-reviewed

Research Article

Nina-Emily Hengartner,

Affiliation Orthopedic Department, Division for Biochemistry of Joint and Connective Tissue Diseases, University of Ulm, Ulm, Germany
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Jörg Fiedler,

Affiliation Orthopedic Department, Division for Biochemistry of Joint and Connective Tissue Diseases, University of Ulm, Ulm, Germany
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Hubert Schrezenmeier,

Affiliation Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service Baden-Württemberg—Hessen and University Hospital Ulm, University of Ulm, Ulm, Germany
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Markus Huber-Lang,

Affiliation Department of Orthopedic Trauma, Hand-, Plastic and Reconstructive Surgery, University of Ulm, Ulm, Germany
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Rolf E. Brenner

* E-mail: rolf.brenner@uni-ulm.de

Affiliation Orthopedic Department, Division for Biochemistry of Joint and Connective Tissue Diseases, University of Ulm, Ulm, Germany
⨯

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Inflammation
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Gene expression
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Enzyme-linked immunoassays
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Macrophages
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Cytokines
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Alizarin staining
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Chemotaxis
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Systemic inflammatory response syndrome
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