Comparative Analysis of Super-Shedder Strains of Escherichia coli O157:H7 Reveals Distinctive Genomic Features and a Strongly Aggregative Adherent Phenotype on Bovine Rectoanal Junction Squamous Epithelial Cells

• Rebecca Cote ,

  ¶‡ These authors contributed equally to this work.

  Affiliations Department of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, United States of America, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Robab Katani ,

  ¶‡ These authors contributed equally to this work.

  Affiliation Department of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Matthew R. Moreau,

  Affiliation Department of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Indira T. Kudva,

  Affiliation Food Safety and Enteric Pathogens Research Unit, National Animal Disease Center, Agricultural Research Service, U.S. Department of Agriculture, Ames, Iowa, United States of America

  ⨯
• Terrance M. Arthur,

  Affiliation Roman L. Hruska U.S. Meat Animal Research Center, Agricultural Research Service, U.S. Department of Agriculture, Clay Center, Nebraska, United States of America

  ⨯
• Chitrita DebRoy,

  Affiliations Department of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, United States of America, E. coli Reference Center, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Michael M. Mwangi,

  Affiliations The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Istvan Albert,

  Affiliations The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Juan Antonio Raygoza Garay,

  Affiliations Department of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, United States of America, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Lingling Li,

  Affiliation Department of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Maria T. Brandl,

  Affiliation Produce Safety and Microbiology, Research Unit, Agriculture Research Service, U.S. Department of Agriculture, Albany, California, United States of America

  ⨯
• Michelle Q. Carter,

  Affiliation Produce Safety and Microbiology, Research Unit, Agriculture Research Service, U.S. Department of Agriculture, Albany, California, United States of America

  ⨯
• Vivek Kapur

  * E-mail: vkapur@psu.edu

  Affiliations Department of Veterinary and Biomedical Science, The Pennsylvania State University, University Park, Pennsylvania, United States of America, The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯