Identification of STAT1 and STAT3 Specific Inhibitors Using Comparative Virtual Screening and Docking Validation

Open Access

Peer-reviewed

Research Article

Malgorzata Szelag,

Affiliation Department of Human Molecular Genetics, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University in Poznan, Umultowska 89, 61-614 Poznan, Poland
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Anna Czerwoniec,

Affiliation Bioinformatics Laboratory, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University in Poznan, Umultowska 89, 61-614 Poznan, Poland
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Joanna Wesoly,

Affiliation Laboratory of High Throughput Technologies, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University in Poznan, Umultowska 89, 61-614 Poznan, Poland
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Hans A. R. Bluyssen

* E-mail: h.bluyss@amu.edu.pl

Affiliation Department of Human Molecular Genetics, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University in Poznan, Umultowska 89, 61-614 Poznan, Poland
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STAT proteins
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SH2 domains
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Crystal structure
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Library screening
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Monomers
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Protein structure
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Protein structure comparison
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Phosphorylation
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