JAK2 Exon 14 Skipping in Patients with Primary Myelofibrosis: A Minor Splice Variant Modulated by the JAK2-V617F Allele Burden

Paolo Catarsi; Vittorio Rosti; Giacomo Morreale; Valentina Poletto; Laura Villani; Roberto Bertorelli; Matteo Pedrazzini; Michele Zorzetto; Giovanni Barosi; AGIMM investigators

doi:10.1371/journal.pone.0116636

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Open Access

Peer-reviewed

Research Article

JAK2 Exon 14 Skipping in Patients with Primary Myelofibrosis: A Minor Splice Variant Modulated by the JAK2-V617F Allele Burden

Paolo Catarsi ,

* E-mail: p.catarsi@smatteo.pv.it

Affiliation Center for the Study and Treatment of Myelofibrosis, Biotechnology Research Laboratories, Fondazione IRCCS “Policlinico San Matteo”, Pavia (PV), Italy
⨯
Vittorio Rosti,

Affiliation Center for the Study and Treatment of Myelofibrosis, Biotechnology Research Laboratories, Fondazione IRCCS “Policlinico San Matteo”, Pavia (PV), Italy
⨯
Giacomo Morreale,

Affiliation Viticulture Research Center, Consiglio per la Ricerca e la sperimentazione in Agricoltura, Conegliano (TV), Italy
⨯
Valentina Poletto,

Affiliation Center for the Study and Treatment of Myelofibrosis, Biotechnology Research Laboratories, Fondazione IRCCS “Policlinico San Matteo”, Pavia (PV), Italy
⨯
Laura Villani,

Affiliation Center for the Study and Treatment of Myelofibrosis, Biotechnology Research Laboratories, Fondazione IRCCS “Policlinico San Matteo”, Pavia (PV), Italy
⨯
Roberto Bertorelli,

Affiliation Laboratory of Biomolecular Sequence and Structure Analysis for Health, Fondazione “Bruno Kessler”, Trento (TN), Italy
⨯
Matteo Pedrazzini,

Affiliation Cardiovascular Genetics Laboratory, Biomedical and Technology Research Centre, Istituto Auxologico Italiano, Cusano Milanino (MI), Italy
⨯
Michele Zorzetto,

Affiliation Laboratory of Biochemistry and Genetics, Division of Pneumology, Department of Molecular Medicine, Fondazione IRCCS “Policlinico San Matteo”, Pavia (PV), Italy
⨯
Giovanni Barosi,

Affiliation Center for the Study and Treatment of Myelofibrosis, Biotechnology Research Laboratories, Fondazione IRCCS “Policlinico San Matteo”, Pavia (PV), Italy
⨯
AGIMM investigators

JAK2 Exon 14 Skipping in Patients with Primary Myelofibrosis: A Minor Splice Variant Modulated by the JAK2-V617F Allele Burden

Paolo Catarsi,
Vittorio Rosti,
Giacomo Morreale,
Valentina Poletto,
Laura Villani,
Roberto Bertorelli,
Matteo Pedrazzini,
Michele Zorzetto,
Giovanni Barosi,
AGIMM investigators

Published: January 24, 2015
https://doi.org/10.1371/journal.pone.0116636

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