Chronic Ingestion of Advanced Glycation End Products Induces Degenerative Spinal Changes and Hypertrophy in Aging Pre-Diabetic Mice

Svenja Illien-Jünger; Young Lu; Sheeraz A. Qureshi; Andrew C. Hecht; Weijing Cai; Helen Vlassara; Gary E. Striker; James C. Iatridis

doi:10.1371/journal.pone.0116625

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Peer-reviewed

Research Article

Chronic Ingestion of Advanced Glycation End Products Induces Degenerative Spinal Changes and Hypertrophy in Aging Pre-Diabetic Mice

Svenja Illien-Jünger ,

¶‡ These authors contributed equally to this work.

Affiliation Leni & Peter W. May Department of Orthopaedics/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯
Young Lu ,

¶‡ These authors contributed equally to this work.

Affiliation Leni & Peter W. May Department of Orthopaedics/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯
Sheeraz A. Qureshi,

Affiliation Leni & Peter W. May Department of Orthopaedics/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯
Andrew C. Hecht,

Affiliation Leni & Peter W. May Department of Orthopaedics/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯
Weijing Cai,

Affiliation Department of Geriatrics and Palliative Care, Division of Experimental Diabetes and Aging/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯
Helen Vlassara,

Affiliation Department of Geriatrics and Palliative Care, Division of Experimental Diabetes and Aging/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯
Gary E. Striker,

Affiliation Department of Geriatrics and Palliative Care, Division of Experimental Diabetes and Aging, and Division of Nephrology, Department of Medicine/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯
James C. Iatridis

* E-mail: james.iatridis@mssm.edu

Affiliation Leni & Peter W. May Department of Orthopaedics/Icahn School of Medicine at Mount Sinai, New York, NY, United States of America
⨯

Chronic Ingestion of Advanced Glycation End Products Induces Degenerative Spinal Changes and Hypertrophy in Aging Pre-Diabetic Mice

Svenja Illien-Jünger,
Young Lu,
Sheeraz A. Qureshi,
Andrew C. Hecht,
Weijing Cai,
Helen Vlassara,
Gary E. Striker,
James C. Iatridis

Published: February 10, 2015
https://doi.org/10.1371/journal.pone.0116625

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