UFSRAT: Ultra-Fast Shape Recognition with Atom Types –The Discovery of Novel Bioactive Small Molecular Scaffolds for FKBP12 and 11βHSD1

Open Access

Peer-reviewed

Research Article

Steven Shave ,

¶‡ These authors contributed equally to this work.

Affiliation Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Elizabeth A. Blackburn ,

¶‡ These authors contributed equally to this work.

Affiliation Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Jillian Adie,

Affiliation Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Douglas R. Houston,

Affiliation Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Manfred Auer,

Affiliation Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Scott P. Webster,

Affiliation University/BHF Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
⨯
Paul Taylor,

Affiliation Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom
⨯
Malcolm D. Walkinshaw

* E-mail: m.walkinshaw@ed.ac.uk

Affiliation Centre for Translational and Chemical Biology, University of Edinburgh, Edinburgh, United Kingdom
⨯

Reader Comments (0)

Electrospray ionization mass spectrometry
Is the Subject Area "Electrospray ionization mass spectrometry" applicable to this article?

Thanks for your feedback.
Hydrogen bonding
Is the Subject Area "Hydrogen bonding" applicable to this article?

Thanks for your feedback.
Cortisol
Is the Subject Area "Cortisol" applicable to this article?

Thanks for your feedback.
Database searching
Is the Subject Area "Database searching" applicable to this article?

Thanks for your feedback.
Protein concentration assays
Is the Subject Area "Protein concentration assays" applicable to this article?

Thanks for your feedback.
Small molecules
Is the Subject Area "Small molecules" applicable to this article?

Thanks for your feedback.
Drug interactions
Is the Subject Area "Drug interactions" applicable to this article?

Thanks for your feedback.
Electrostatics
Is the Subject Area "Electrostatics" applicable to this article?

Thanks for your feedback.