Frostbite Protection in Mice Expressing an Antifreeze Glycoprotein

Martin Heisig; Sarah Mattessich; Alison Rembisz; Ali Acar; Martin Shapiro; Carmen J. Booth; Girish Neelakanta; Erol Fikrig

doi:10.1371/journal.pone.0116562

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Peer-reviewed

Research Article

Frostbite Protection in Mice Expressing an Antifreeze Glycoprotein

Martin Heisig,

Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States of America
⨯
Sarah Mattessich,

Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States of America
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Alison Rembisz,

Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States of America
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Ali Acar,

Affiliations Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States of America, Department of Infectious Disease and Clinical Microbiology, Gulhane Military Medical Academy, Haydarpasa Training Hospital, Istanbul, Turkey
⨯
Martin Shapiro,

Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States of America
⨯
Carmen J. Booth,

Affiliation Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT, United States of America
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Girish Neelakanta,

Current address: Center for Molecular Medicine, Department of Biological Sciences, Old Dominion University, Norfolk, VA, United States of America

Affiliation Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States of America
⨯
Erol Fikrig

* E-mail: erol.fikrig@yale.edu

Affiliations Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT, United States of America, Howard Hughes Medical Institute, Chevy Chase, MD, United States of America
⨯

Frostbite Protection in Mice Expressing an Antifreeze Glycoprotein

Martin Heisig,
Sarah Mattessich,
Alison Rembisz,
Ali Acar,
Martin Shapiro,
Carmen J. Booth,
Girish Neelakanta,
Erol Fikrig

Published: February 25, 2015
https://doi.org/10.1371/journal.pone.0116562

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Genetically modified animals
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Antifreeze proteins
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Cytokines
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Fibroblasts
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Inflammation
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Mouse models
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Glycoproteins
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Specimen storage
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