Reduced Parasite Motility and Micronemal Protein Secretion by a p38 MAPK Inhibitor Leads to a Severe Impairment of Cell Invasion by the Apicomplexan Parasite Eimeria tenella

Françoise I. Bussière; Fabien Brossier; Yves Le Vern; Alisson Niepceron; Anne Silvestre; Thibaut de Sablet; Sonia Lacroix-Lamandé; Fabrice Laurent

doi:10.1371/journal.pone.0116509

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Research Article

Reduced Parasite Motility and Micronemal Protein Secretion by a p38 MAPK Inhibitor Leads to a Severe Impairment of Cell Invasion by the Apicomplexan Parasite Eimeria tenella

Françoise I. Bussière ,

* E-mail: Francoise.Bussiere@tours.inra.fr

Affiliations Apicomplexes et Immunité Mucosale, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France, Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France
⨯
Fabien Brossier †,

† Deceased.

Affiliations Apicomplexes et Immunité Mucosale, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France, Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France
⨯
Yves Le Vern,

Affiliations Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France, Plate-forme d’Analyse Intégrative des Biomolécules, Laboratoire de Cytométrie et Fluorimétrie, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France
⨯
Alisson Niepceron,

Affiliations Apicomplexes et Immunité Mucosale, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France, Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France
⨯
Anne Silvestre,

Affiliations Apicomplexes et Immunité Mucosale, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France, Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France
⨯
Thibaut de Sablet,

Affiliations Apicomplexes et Immunité Mucosale, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France, Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France
⨯
Sonia Lacroix-Lamandé,

Affiliations Apicomplexes et Immunité Mucosale, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France, Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France
⨯
Fabrice Laurent

Affiliations Apicomplexes et Immunité Mucosale, INRA, UMR1282, Infectiologie et Santé Publique, F-37380 Nouzilly, France, Université François Rabelais de Tours, UMR1282, Infectiologie et Santé Publique, F-37000 Tours, France
⨯

Reduced Parasite Motility and Micronemal Protein Secretion by a p38 MAPK Inhibitor Leads to a Severe Impairment of Cell Invasion by the Apicomplexan Parasite Eimeria tenella

Françoise I. Bussière,
Fabien Brossier,
Yves Le Vern,
Alisson Niepceron,
Anne Silvestre,
Thibaut de Sablet,
Sonia Lacroix-Lamandé,
Fabrice Laurent

Published: February 17, 2015
https://doi.org/10.1371/journal.pone.0116509

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