Anti-Lubricin Monoclonal Antibodies Created Using Lubricin-Knockout Mice Immunodetect Lubricin in Several Species and in Patients with Healthy and Diseased Joints

• Minrong Ai,

  Current Address: Department of Musculoskeletal Research, Lilly Research Laboratories, Indianapolis, IN, United States of America

  Affiliation Howard Hughes Medical Institute and Department of Genetics, Case Western Reserve University, School of Medicine, Cleveland, OH, United States of America

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• Yajun Cui,

  Current Address: Harvard School of Dental Medicine, Boston, MA, United States of America

  Affiliation Howard Hughes Medical Institute and Department of Genetics, Case Western Reserve University, School of Medicine, Cleveland, OH, United States of America

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• Man-Sun Sy,

  Affiliation Department of Pathology, Case Western Reserve University, School of Medicine, Cleveland, OH, United States of America

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• David M. Lee,

  Current Address: Novartis Institutes for Biomedical Research, Basel, Switzerland

  Affiliation Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, United States of America

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• Ling Xiu Zhang,

  Affiliation Department of Emergency Medicine, Rhode Island Hospital, Providence, RI, United States of America

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• Katherine M. Larson,

  Affiliations Department of Emergency Medicine, Rhode Island Hospital, Providence, RI, United States of America, School of Engineering, Brown University, Providence, RI, United States of America

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• Kyle C. Kurek,

  Current Address: Department of Pathology & Laboratory Medicine, University of Calgary, Calgary, Canada

  Affiliation Department of Pathology, Boston Children’s Hospital, Boston, MA, United States of America

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• Gregory D. Jay,

  Affiliations Department of Emergency Medicine, Rhode Island Hospital, Providence, RI, United States of America, School of Engineering, Brown University, Providence, RI, United States of America

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• Matthew L. Warman

  * E-mail: matthew.warman@childrens.harvard.edu

  Current Address: Boston Children’s Hospital, Boston, MA, United States of America

  Affiliations Howard Hughes Medical Institute and Department of Genetics, Case Western Reserve University, School of Medicine, Cleveland, OH, United States of America, Howard Hughes Medical Institute and Orthopaedics Research Laboratories, Boston Children’s Hospital, and Departments of Genetics and Orthopaedic Surgery, Harvard Medical School, Boston, MA, United States of America

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