Crystal Structure of Human Importin-α1 (Rch1), Revealing a Potential Autoinhibition Mode Involving Homodimerization

• Hideyuki Miyatake ,

  * E-mail: miyatake@riken.jp (HM); aida@riken.jp (YA)

  Affiliation Global Research Cluster Collaboration Promotion Unit, RIKEN, 2–1, Hirosawa, Wako-shi, Saitama 351–0198, Japan

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• Akira Sanjoh,

  Affiliation Protein Wave Corporation, 1–16–5 Nishitomigaoka, Nara 631–0006, Japan

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• Satoru Unzai,

  Affiliation Graduate School of Medical Life Science, Yokohama City University, 1–7–29 Suehiro-cho, Tsurumi-ku, Yokohama 230–0045, Japan

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• Go Matsuda,

  Affiliation Viral Infectious Diseases Unit, RIKEN, 2–1, Hirosawa, Wako-shi 351–0198, Japan

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• Yuko Tatsumi,

  Affiliation Protein Wave Corporation, 1–16–5 Nishitomigaoka, Nara 631–0006, Japan

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• Yoichi Miyamoto,

  Affiliations Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Building 76 Level 2, Wellington Road, Clayton VIC 3800, Australia, Laboratory of Nuclear Transport Dynamics, National Institute of Biomedical Innovation, 7–6–8 Saito-Asagi, Ibaraki-shi, Osaka 567–0085, Japan

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• Naoshi Dohmae,

  Affiliation Global Research Cluster Collaboration Promotion Unit, RIKEN, 2–1, Hirosawa, Wako-shi, Saitama 351–0198, Japan

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• Yoko Aida

  * E-mail: miyatake@riken.jp (HM); aida@riken.jp (YA)

  Affiliation Viral Infectious Diseases Unit, RIKEN, 2–1, Hirosawa, Wako-shi 351–0198, Japan

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