pH-Dependent Conformational Changes in the HCV NS3 Protein Modulate Its ATPase and Helicase Activities

Open Access

Peer-reviewed

Research Article

Gustavo Tavares Ventura,

Affiliation Laboratório de Genômica Estrutural, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
⨯
Emmerson Corrêa Brasil da Costa,

Current address: Centro de Ciências da Saúde e do Desporto (UFAC-CCSD) da Universidade Federal do Acre, Rio Branco, AC, Brazil

Affiliation Laboratório de Genômica Estrutural, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
⨯
Anne Miranda Capaccia,

Affiliation Laboratório de Genômica Estrutural, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
⨯
Ronaldo Mohana-Borges

* E-mail: mohana@biof.ufrj.br

Affiliation Laboratório de Genômica Estrutural, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
⨯

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Helicases
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Denaturation
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Adenosine triphosphatase
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Proteases
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Nucleic acids
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Fluorescence
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Anisotropy
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DNA-binding proteins
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