A Cyclic Peptidic Serine Protease Inhibitor: Increasing Affinity by Increasing Peptide Flexibility

• Baoyu Zhao ,

  Contributed equally to this work with: Baoyu Zhao, Peng Xu

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, China

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• Peng Xu ,

  Contributed equally to this work with: Baoyu Zhao, Peng Xu

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

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• Longguang Jiang,

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, China

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• Berit Paaske,

  Affiliation Nanoscience Center and Department of Chemistry, University of Aarhus, Aarhus, Denmark

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• Tobias Kromann-Hansen,

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

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• Jan K. Jensen,

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

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• Hans Peter Sørensen,

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

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• Zhuo Liu,

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

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• Jakob T. Nielsen,

  Affiliation Nanoscience Center and Department of Chemistry, University of Aarhus, Aarhus, Denmark

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• Anni Christensen,

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

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• Masood Hosseini,

  Affiliation Department of Chemistry, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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• Kasper K. Sørensen,

  Affiliation Department of Chemistry, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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• Niels Christian Nielsen,

  Affiliation Nanoscience Center and Department of Chemistry, University of Aarhus, Aarhus, Denmark

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• Knud J. Jensen,

  Affiliation Department of Chemistry, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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• Mingdong Huang,

  Affiliation Danish-Chinese Centre for Proteases and Cancer, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, China

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•  [ ... ],
• Peter A. Andreasen

  * E-mail: pa@mbg.au.dk

  Affiliations Danish-Chinese Centre for Proteases and Cancer, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, China, Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark

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