Bladder Cancer Biomarker Discovery Using Global Metabolomic Profiling of Urine

Bryan M. Wittmann; Steven M. Stirdivant; Matthew W. Mitchell; Jacob E. Wulff; Jonathan E. McDunn; Zhen Li; Aphrihl Dennis-Barrie; Bruce P. Neri; Michael V. Milburn; Yair Lotan; Robert L. Wolfert

doi:10.1371/journal.pone.0115870

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Open Access

Peer-reviewed

Research Article

Bladder Cancer Biomarker Discovery Using Global Metabolomic Profiling of Urine

Bryan M. Wittmann ,

* E-mail: bwittmann@metabolon.com

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Steven M. Stirdivant,

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Matthew W. Mitchell,

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Jacob E. Wulff,

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Jonathan E. McDunn,

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Zhen Li,

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Aphrihl Dennis-Barrie,

Affiliation Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Bruce P. Neri,

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Michael V. Milburn,

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯
Yair Lotan,

Affiliation Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Robert L. Wolfert

Affiliation Clinical Research and Development, Metabolon Inc., Durham, North Carolina, United States of America
⨯

Bladder Cancer Biomarker Discovery Using Global Metabolomic Profiling of Urine

Bryan M. Wittmann,
Steven M. Stirdivant,
Matthew W. Mitchell,
Jacob E. Wulff,
Jonathan E. McDunn,
Zhen Li,
Aphrihl Dennis-Barrie,
Bruce P. Neri,
Michael V. Milburn,
Yair Lotan

Published: December 26, 2014
https://doi.org/10.1371/journal.pone.0115870

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Urine
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Bladder cancer
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Metabolites
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Biomarkers
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Cancer detection and diagnosis
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Xenobiotic metabolism
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