Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice

Hong-Min Ni; Amar Bhakta; Shaogui Wang; Zhenrui Li; Sharon Manley; Heqing Huang; Bryan Copple; Wen-Xing Ding

doi:10.1371/journal.pone.0115849

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Peer-reviewed

Research Article

Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice

Hong-Min Ni,

Affiliation Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Amar Bhakta,

Affiliation Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Shaogui Wang,

Affiliations Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, United States of America, Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Zhenrui Li,

Affiliation Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Sharon Manley,

Affiliation Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Heqing Huang,

Affiliation Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China
⨯
Bryan Copple,

Current address: Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan, United States of America

Affiliation Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯
Wen-Xing Ding

* E-mail: wxding@kumc.edu

Affiliation Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, United States of America
⨯

Role of Hypoxia Inducing Factor-1β in Alcohol-Induced Autophagy, Steatosis and Liver Injury in Mice

Hong-Min Ni,
Amar Bhakta,
Shaogui Wang,
Zhenrui Li,
Sharon Manley,
Heqing Huang,
Bryan Copple,
Wen-Xing Ding

Published: December 23, 2014
https://doi.org/10.1371/journal.pone.0115849

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Ethanol
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