Neither the HIV Protease Inhibitor Lopinavir-Ritonavir nor the Antimicrobial Trimethoprim-Sulfamethoxazole Prevent Malaria Relapse in Plasmodium cynomolgi-Infected Non-Human Primates

Charlotte V. Hobbs; Saurabh Dixit; Scott R. Penzak; Tejram Sahu; Sachy Orr-Gonzalez; Lynn Lambert; Katie Zeleski; Jingyang Chen; Jillian Neal; William Borkowsky; Yimin Wu; Patrick E. Duffy

doi:10.1371/journal.pone.0115506

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Open Access

Peer-reviewed

Research Article

Neither the HIV Protease Inhibitor Lopinavir-Ritonavir nor the Antimicrobial Trimethoprim-Sulfamethoxazole Prevent Malaria Relapse in Plasmodium cynomolgi-Infected Non-Human Primates

Charlotte V. Hobbs ,

* E-mail: charlotte.hobbs@nih.gov

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Saurabh Dixit,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Scott R. Penzak,

Affiliation Department of Pharmacotherapy, University of North Texas System College of Pharmacy, Fort Worth, Texas, 76107, United States of America
⨯
Tejram Sahu,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Sachy Orr-Gonzalez,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Lynn Lambert,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Katie Zeleski,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Jingyang Chen,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Jillian Neal,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
William Borkowsky,

Affiliation Department of Pediatrics, Division of Infectious Disease and Immunology, New York University School of Medicine, New York, New York, United States of America
⨯
Yimin Wu,

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Patrick E. Duffy

Affiliation Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, United States of America
⨯

Neither the HIV Protease Inhibitor Lopinavir-Ritonavir nor the Antimicrobial Trimethoprim-Sulfamethoxazole Prevent Malaria Relapse in Plasmodium cynomolgi-Infected Non-Human Primates

Charlotte V. Hobbs,
Saurabh Dixit,
Scott R. Penzak,
Tejram Sahu,
Sachy Orr-Gonzalez,
Lynn Lambert,
Katie Zeleski,
Jingyang Chen,
Jillian Neal,
William Borkowsky

Published: December 26, 2014
https://doi.org/10.1371/journal.pone.0115506

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