Inhibition of Nicotinic Acetylcholine Receptors, a Novel Facet in the Pleiotropic Activities of Snake Venom Phospholipases A2

Catherine A. Vulfius; Igor E. Kasheverov; Vladislav G. Starkov; Alexey V. Osipov; Tatyana V. Andreeva; Sergey Yu. Filkin; Elena V. Gorbacheva; Maxim E. Astashev; Victor I. Tsetlin; Yuri N. Utkin

doi:10.1371/journal.pone.0115428

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Peer-reviewed

Research Article

Inhibition of Nicotinic Acetylcholine Receptors, a Novel Facet in the Pleiotropic Activities of Snake Venom Phospholipases A₂

Catherine A. Vulfius,

Affiliation Institute of Cell Biophysics, Russian Academy of Sciences, Ul. Institutskaya 3, Pushchino, Moscow Region 142290, Russia
⨯
Igor E. Kasheverov,

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia
⨯
Vladislav G. Starkov,

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia
⨯
Alexey V. Osipov,

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia
⨯
Tatyana V. Andreeva,

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia
⨯
Sergey Yu. Filkin,

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia
⨯
Elena V. Gorbacheva,

Affiliation Institute of Cell Biophysics, Russian Academy of Sciences, Ul. Institutskaya 3, Pushchino, Moscow Region 142290, Russia
⨯
Maxim E. Astashev,

Affiliation Institute of Cell Biophysics, Russian Academy of Sciences, Ul. Institutskaya 3, Pushchino, Moscow Region 142290, Russia
⨯
Victor I. Tsetlin,

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia
⨯
Yuri N. Utkin

* E-mail: utkin@mx.ibch.ru

Affiliation Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Ul. Miklukho-Maklaya 16/10, Moscow 117997, Russia
⨯

Inhibition of Nicotinic Acetylcholine Receptors, a Novel Facet in the Pleiotropic Activities of Snake Venom Phospholipases A₂

Catherine A. Vulfius,
Igor E. Kasheverov,
Vladislav G. Starkov,
Alexey V. Osipov,
Tatyana V. Andreeva,
Sergey Yu. Filkin,
Elena V. Gorbacheva,
Maxim E. Astashev,
Victor I. Tsetlin,
Yuri N. Utkin

Published: December 18, 2014
https://doi.org/10.1371/journal.pone.0115428

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Nicotinic acetylcholine receptors
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Neurons
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Venoms
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Snakes
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Acetylcholine
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Phospholipases
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Receptor binding assays
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Cell binding assay
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